Almost all treatments and drugs produce potentially unwanted side effects.

Most side effects following a SIRT procedure are minor., making patients feel uncomfortable, but a small number can be serious. Every patient is different in how he or she reacts to a treatment. 

Patients may experience

  • abdominal pain or tightness in their abdomen,
  • nausea and loss of appetite which normally subsides within a week after treatment
  • mild fever that may last for up to a week
  • fatigue, which may last for several weeks post-treatment.

As a precaution, specific peri-procedural medications are prescribed to control these symptoms.

In rare instances, there is a possibility that microspheres may inadvertently reach other organs in the body, such as the gallbladder, stomach, intestine, or pancreas.

  • If SIR-Spheres® Y-90 resin microspheres reach these organs, they may cause cholecystitis, gastritis, duodentitis or pancreatitis.
  • These complications are rare, but if they do occur they may require additional medical treatment.

Between 60 and 90 days post treatment, there is also a small risk of radioembolisation induced liver disease (REILD) which is characterised by jaundice, ascites and elevated bilirubin levels.

​For more information please see Approved Indication.




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