William “Pepper” Denman

Global Chief Medical Officer

Experience and Expertise

A highly motivated business partner with a proven ability to drive revenue, Pepper has provided strategic leadership to medical companies at every stage from startup to exit.

Since joining Sirtex in 2018, Pepper has taken a lead role in determining medical and clinical strategy. He specializes in driving data-generated value propositions and ensuring clinical trials remain focused on growth.

Outside of a five-year stint as Chief of Pediatric Anesthesia at Floating Hospital for Children and Associate Professor at Tufts University School of Medicine, Pepper has been an Attending Anesthesiologist at Massachusetts General Hospital and a lecturer at Harvard Medical School since 1990. In addition to being the Principal at Denman Associates since 2012 where he provided strategic consulting services, he has served as Chief Medical Officer at both GE Healthcare and Covidien, as well as several smaller start-ups.

Pepper attended George Watson's College along with the University of Aberdeen, where he earned his Doctor of Medicine in 1985. A member of both the American Society of Anesthesiology and International Anesthesia Research Society, he also serves as Editor of International Anesthesia Clinics. He has been co-leader of a charity mission to Vietnam for facial reconstructive surgery since 1999.



Kevin R. Smith

William “Pepper” Denman
Global Chief Medical Officer

Anthony Dixon
Executive Vice President of Sales and Marketing EMEA

Donna Fort
Executive Vice President Sales & Marketing-APAC

Cathleen Lowndes
Chief Human Resources Officer

Amy Pan
Chief Financial Officer

Suki Shergill
Executive Vice President, Global Pricing & Market Access

Kevin P. Smith
General Counsel & Executive Vice President, Business Development

Grant Spindler
Global Head of Operations

MaryLou Stroumbos
Vice President, Regulatory Affairs & Quality Assurance

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