Dados publicados no melanoma ocular metastático

As microesferas de resina SIR-Spheres® Y-90 mostraram benefícios no tratamento de primeira linha de metástases hepáticas refratárias ao tratamento de melanoma (predominantemente de tumores primários oculares ou uveais).

Em uma população mista de pacientes com melanoma cutâneo ou ocular metastático irressecável que era refratária à terapia sistêmica, as microesferas de resina SIR-Spheres Y-90 foram associadas com maior sobrevida a partir do diagnóstico do melanoma metastático do que o melhor tratamento de suporte (19.9 months vs. 4.8 months).1 Outros estudos não comparativos de SIRT com microesferas de resina SIR-Spheres Y-90 para melanoma metastático demonstraram sobrevida semelhante ou mais longa a partir do diagnóstico (19,0 a 23,9 meses).2,3

As microesferas de resina SIR-Spheres Y-90 são geralmente bem toleradas neste cenário clínico.

1 Xing M. et al. Am J Clin Oncol 2014 Aug 1; ePub doi: 10.1097/COC.0000000000000109.
2 Klingenstein A. et al. Cardiovasc Intervent Radiol 2013; 36: 158-165.
3 Eldredge-Hindy H. et al. Am J Clin Oncol 2016; 39: 189-195.

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