Principais conclusões

  • Pacientes com mCRC com tumores primários no cólon direito são relativamente resistentes aos tratamentos de quimioterapia sistêmica padrão de atendimento e apresentam pior prognóstico1-3
  • O tratamento desses pacientes com quimioterapia à base de FOLFOX + SIRT usando microesferas de resina SIR-Spheres® Y-90 em primeira linha resultou em uma melhora estatisticamente significativa (p<0,0008) e clinicamente significativa (HR = 0,64) na sobrevida global em comparação à quimioterapia isoladamente, como demonstrado em uma análise post hoc de subgrupos4

1. Tejpar S et al.  JAMA Oncol 2017; 3: 194-201.
2. Petrelli F et al. JAMA Oncol 2017; 3: 211–19.
3. Venook AP et al. Proc Am Soc Clin Oncol 2016; 34 (suppl 15): 3504 (abstr).
4. Gibbs P et al.  Clin Col Cancer 2018 Jun 12 ePub: doi: 10.1016/j.clcc.2018.06.001.


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