Clinicians > HCC Clinical Studies > SARAH >
Safety and Tolerability


SIR-Spheres® Y-90 resin microspheres were significantly better tolerated than sorafenib in the safety population:

Significantly fewer and less severe Adverse Events (AE)



Significantly fewer patients with treatment-related AEs



Median treatment-related AEs per patient



Significantly reduced frequency and severity of AEs



Overview of the adverse events in the Safety population

SIR-Spheres Y-90 resin microspheres were safe and well tolerated, with few SIRT associated complications

There was no treatment related radiation hepatitis or radioembolisation induced liver disease.

Vilgrain V et al.  Lancet Oncol 2017; 18: 1624–36.
Bouattour M et al.  Ann Oncol 2017; ESMO 19th WCGIC, Abs. LBA-001.




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