Response after treatment with SIR-Spheres® Y-90 resin microspheres may be evaluated by CT, MRI, PET and/or changes in tumor markers.
Anatomical criteria (Response Evaluation Criteria In Solid Tumors - RECIST) can be misleading and may lead to an underestimation of the pathological tumor response, especially if determined early (<3 months). Imaging evaluation that incorporated necrosis indicators reported that response to treatment can become apparent earlier (one month).1
1. Keppke et al. Am J Roentgenol 2007; 188: 768-775.